BUCCAL meaning: 1. relating to the inside of the mouth, especially the cheek 2. relating to the inside of the…. Learn more. Define buccal. buccal synonyms, buccal pronunciation, buccal translation, English dictionary definition of buccal. adj. Of or relating to the cheeks or the mouth cavity. buc′cal·ly adv. American Heritage® Dictionary of the English Language, Fifth Edition. Looking for online definition of buccal in the Medical Dictionary? buccal explanation free. What is buccal? Meaning of buccal medical term. What does buccal mean? BUCCAL definition: of or relating to the cheek. See examples of buccal used in a sentence. In a medical context, “buccal” is a directional term meaning pertaining to or directed toward the cheek. It describes the tissues and structures adjacent to the inner lining of the cheek, such as the buccal mucosa (the moist mucous membrane lining the inside of the cheek). of or relating to or toward the cheek The meaning of BUCCAL is of, relating to, near, involving, or supplying a cheek. How to use buccal in a sentence. Buccal administration Buccal administration is a topical route of administration by which particular drugs held or applied in the buccal (/ ˈbʌkəl /) area (in the cheek) will diffuse through the oral mucosa — (tissues that line the mouth) — and will thereby enter directly into the bloodstream. The term buccal surface is used for the surfaces of the premolars and molars that are immediately adjacent to the cheek. The labial and buccal surfaces are collectively known as the tooth’s facial (face) surfaces. BUCCAL definition: 1. relating to the inside of the mouth, especially the cheek 2. relating to the inside of the…. Learn more.